The Kenai Post 20 Twins fell to Kennewick, the Washington state champions, 16-2 in seven innings, Wednesday in Cheyenne, Wyoming.
The Twins committed seven errors as the Outlaws raced out to a 13-0 lead.
Kenai (32-9) plays in a loser-out game today at 10:30 a.m.
The Twins are now 0-9 in Outside games after winning state titles in 1991, 1995 and 2012 and after a runner-up finish in 2015.
Joe Becher struggled on the mound, allowing 11 runs on seven hits in four innings. Justice Miller and J.J. Sonnen, who hit a double, also pitched.
Kennewick rode into the regional tournament with a 16-game winning streak and a 50-13 record.
The Outlaws scored in every inning but one, while the Twins scored solo runs in the fifth and seventh innings.